Effects of propofol on respiratory mechanic and lung histology in normal rats

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Effects of propofol on respiratory mechanic and lung histology in normal rats.

BACKGROUND Propofol is able to reduce airway resistance in lungs with previous airway constriction. The aim of this study was to evaluate the effects of propofol on respiratory mechanics in normal rats and to correlate these parameters with lung histology, to define the sites of action of propofol. METHODS Sixteen Wistar rats were divided into two groups of eight animals. Rats were sedated (d...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2004

ISSN: 0007-0912

DOI: 10.1093/bja/aeh128